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Omeprazole Capsules are proton pump inhibitors that are prescribed for treatment of peptic ulcer disease, Zollinger-Ellison syndrome, erosive esophagitis, GERD, and upper gastrointestinal bleeding. Upon ingestion, they get absorbed in parietal cells of stomach and bind to H+/K+ ATPase pump and prevent secretion of gastric acid. These capsules get metabolized in liver with help of CYP2C19 & CYP3A4 with elimination half life of about 1 to 1.2 hours. Omeprazole Capsules shows bioavailability of up to 75% with protein binding ability of 95%. Absorption of this medicine takes place in small intestine with excretion in urine & feces.
Omeprazole & Domperidone Capsules IP